Why PRP for Sexual Health is the best thing you’ve probably never heard of

I’ll cut right to the chase. Women’s choices for managing and treating their libido and sexual health are limited. Health care dollars have not prioritized women’s sexual health and pleasure systems. And this is demonstrated by the paucity of choices for the treatment of sexual dysfunction available in 2022.

There are currently two FDA-approved treatments for Hypoactive Sexual Desire Disorder for women on the market Flibanserin (Addyi) and Bremelanotide (Vyleesi) and then we add testosterone (non-FDA approved) – and while testosterone CAN be amazing – it isn’t for everyone. Next, we contemplate what we can do with our minds, thoughts, emotions and our head starts to spin… Although that introspective work is probably the MOST important key to sexual health and success. More on that in another blog.

So what are our choices if we want to stay clear of medications and hormones? Natural products? Yep, definitely worth a try. Herbs and botanicals can be helpful but they tend to work best in mild cases and usually take several months to see the effect, speaking from my clinical experience here

So what’s a girl to do to get a good orgasm around here? Think about what your own body is already naturally producing for you – Platelet Rich Plasma for sexual enhancement.


The research behind PRP for Female Orgasm Enhancement and Urinary Incontinence in Women


One of the biggest criticisms of the PRP shot for sexual enhancement is there is “no research” to support its claims of better orgasms, lubrication, and enhanced vaginal tone among other benefits. Providers unfamiliar with the procedure or simply unread on the topic, scoff that injecting your OWN blood components back into your own genital tissue, could have any benefit. Well, you judge for yourself but there are more than a dozen research papers on this procedure, all supporting the procedure as safe and effective at helping women achieve better sex lives without drugs or surgery. I have personally witnessed this being life-changing for my female patients and encourage patients and providers to do their homework before they write this brilliant procedure off due to “lack of research”.

The PRP shot for women is a simple 5-minute procedure (30 minutes if you include the blood draw and numbing agent), that can be transformative for women postpartum through menopause to achieve better sexual health and vitality with themselves and their partners.

Let’s start with a recap of WHAT IS PRP?

This magical substance is found in our bloodstream and, when concentrated using a special type of tube, it boasts contents that promote healing and rejuvenation of the tissue. Want details? Ok…you asked for it. PRP contains “Insulin-like growth factor (IGF), epidermal growth factor (EGF), basic fibroblast growth factor (bFGF), platelet-derived growth factor (PDGF), transforming growth factor-beta (TGF-β), vascular endothelial growth factors (VEGF), connective tissue growth factor (CTGF) hepatocyte growth factor (HGF) and interleukin 8 (IL-8) to name a few” (Long et al., 2021). Each one of these components plays an important role to bring cells to the area that needs more scaffolding, tissue repair, and new blood cells.

In a study published in March 2021 out of Egypt authors note “after PRP injection, vaginal vascularity is increased, with a subsequent dramatic increase insensitivity. In addition, the ligaments and muscle supporting the urethra become stronger, alleviating urinary incontinence” (Gaber et al., 2021).

Their results on patients demonstrated a 64% improvement in symptoms including arousal, lubrication, orgasm, satisfaction, and pain.

Another article, published in 2019 by Kaur et al describes PRP for vaginal rejuvenation and sexual enhancement as follows “PRP for the rejuvenation of vaginal mucosa, muscles, and skin. Following PRP injection, an increase in vaginal vascularity is improved, with a dramatic increase in sensitivity. Additionally, the skin becomes thicker and firmer, making the vagina look more youthful” (Kauer et al, 2019). Let’s be honest here, the function is a priority but who doesn’t want their lady parts to look “youthful”?

In the largest study to date in Brazil in 2017, the authors found out of the sixty-eight women who participated, 94% of them were satisfied with two separate injections. The authors write “improved vascularity and neuronal regrowth in the vagina and clitoral area could restore or possibly enhance sexual responsiveness and sensitivity by increasing blood flow. Collagen and sensory nerve regrowth might relieve coital discomfort as well as enhance vaginal sensitivity” (Neto JB., 2017).

In the article published in Journal of Women’s Health Care and authored by the creator of the “O-Shot” Dr. Charles Runels, he enrolled eleven women ages 24-64 and found improvements in arousal, lubrication, desire, pain, and orgasm but did not see changes in satisfaction or pain across all women. One injection was administered to women and follow-up questionnaires were asked twelve to sixteen weeks following the procedure (Runels et al., 2014).

Another study out of Turkey in 2019 (Sukgen et al., 2019) performed four separate PRP injections into the anterior vaginal walls and G-spot to women with diagnosed sexual dysfunction and orgasmic disorder. All women improved over the course of the four procedures in areas of desire, arousal, lubrication, orgasm, satisfaction, and pain. For those nerdy and who want to check out the author’s statistical table, here you go.

There are several other studies I will list in the bibliography for those wishing to read up and if you’re wondering if the research exists for men too. It absolutely does.

The point of all this is the PRP for female sexual enhancement is worthy of consideration procedure in 95% of cases. Now for the downside. It can be pricey. So here is how you get the most bang for your buck.

  • Optimize your health BEFORE you do the procedure. PRP is from your blood, so if you’re not taking great care of yourself prior to the procedure, your outcomes may be less than they could be.
  • Hormones on-board can make your PRP even more responsive. Whether you’re still cycling naturally or using HRT, hormones can make the vaginal and erectile tissues quicker to respond and enhance the rejuvenation effects.
  • Don’t take advil, aleve, or other NSAIDs prior to the procedure. We want your inflammatory response mechanisms working in tip-top shape. Don’t worry, you will be completely numb for the procedure.
  • Get great sleep the night before the procedure. Use visualizations and fantasy to bring more awareness and blood flow to the area of desire.
  • Meet with a Functional Medicine physician prior to your procedure. Optimizing your body will automatically help your PRP become more potent!

I am currently doing consultations for PRP for Sexual Enhancement at Vida Integrated Health for men and women.



Live in Washington State? I am accepting patients for PRP services at Vida Integrated Health in Kirkland, Washington, or Ravenna, Washington. 


Gaber M, Shaltout S. Assessment of autologous platelet-rich plasma as a local therapy for female sexual dysfunction. Menoufia Medical Journal. 2021;34(1):61-65

Kaur Kkochar, Allahbadia G, Singh M. Autologous Platelet rich plasma (PRP)- A Possibility of becoming a revolutionary therapy in the field of Gynaecology and reproductive Endocrinology and Infertility. Progress in Women’s Healthcare. August 2019:1-13. doi:10.33702/pwhc.2019.1.1.1

Long CY, Lin KL, Shen CR, et al. A pilot study: effectiveness of local injection of autologous platelet-rich plasma in treating women with stress urinary incontinence. Scientific reports. 2021;11(1):1584-1584. doi:10.1038/s41598-020-80598-2

JB N. O-Shot: Platelets Rich Plasma in Intimate Female Treatment. Journal of Women’s Health Care. 2017;6(5). doi:10.4172/2167-0420.1000395

Runels C. A Pilot Study of the Effect of Localized Injections of Autologous Platelet Rich Plasma (PRP) for the Treatment of Female Sexual Dysfunction. Journal of Women’s Health Care. 2014;3(4). doi:10.4172/2167-0420.1000169

Sukgen G, Ellibeş Kaya A, Karagün E, Çalışkan E. Platelet-rich plasma administration to the lower anterior vaginal wall to improve female sexuality satisfaction. Turkish journal of obstetrics and gynecology. 2019;16(4):228-234. doi:10.4274/tjod.galenos.2019.23356


Writer: Michelle Leary
Writer: Michelle Leary
March 4, 2022

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